4,179 research outputs found

    Green printing technologies versus traditional printing technologies in sheet-fed offset lithography

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    This experimental study compares green printing technologies (ink and stock) to traditional printing technologies (ink and stock) regarding how they compare in quality. The quality was measured using the print characteristics of gray balance and dot gain. A comparison of the two independent variables (ink and stock) was conducted to determine if a difference exists for the selected characteristics. It has been suggested that the green technologies, despite being more environmentally friendly, are not as high in quality and therefore result in a lower quality printed piece. This research used a four-color test form that was printed using both the green and traditional technologies. The characteristics were measured using an X-rite 528 spectrodensitometer, after which the data were analyzed and conclusions reported. The results of the study suggest that there is no practical significance between the different inks and stocks employed in this study. It was determined however that the best print quality in terms of dot gain (meaning the least amount of dot gain) resulted from the combination of green technologies (ink and paper).Department of TechnologyThesis (M.A.

    The Heart Wants What It Wants: Effects of Desirability and Body Part Salience on Distance Perceptions (Campbell)

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    Previous research has shown that desirability influences perceived distance to an object, such that desirable objects are perceived as closer to the viewer than undesirable objects (Balcetis & Dunning, 2010). Research regarding conceptual metaphors has suggested that making the head or heart salient by placing the index finger there produces characteristics commonly associated with these body parts (i.e., emotionality for the heart and rationality for the head) (Fetterman & Robinson, 2013). The current studies examined the effects of desirability and head or heart salience on distance perception. Participants had their attention drawn to their head or their heart by touching it with their index finger while throwing a beanbag towards a desirable or a neutral object. In Experiment 2, a verbal estimate of distance was also measured. We predicted that, due to the popular association of the heart with desire, there would be a significant interaction between desirability of an object and hand placement. Specifically, there would be no effect of hand placement when the object was neutral, but heart-pointers would perceive the desirable object as closer than head-pointers. Results from both studies failed to support the predictions, as neither hand placement nor object desirability affected distance perceptions. Limitations and suggestions for further research are discussed

    Real-time closed-loop simulation and upset evaluation of control systems in harsh electromagnetic environments

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    Digital control systems for applications such as aircraft avionics and multibody systems must maintain adequate control integrity in adverse as well as nominal operating conditions. For example, control systems for advanced aircraft, and especially those with relaxed static stability, will be critical to flight and will, therefore, have very high reliability specifications which must be met regardless of operating conditions. In addition, multibody systems such as robotic manipulators performing critical functions must have control systems capable of robust performance in any operating environment in order to complete the assigned task reliably. Severe operating conditions for electronic control systems can result from electromagnetic disturbances caused by lightning, high energy radio frequency (HERF) transmitters, and nuclear electromagnetic pulses (NEMP). For this reason, techniques must be developed to evaluate the integrity of the control system in adverse operating environments. The most difficult and illusive perturbations to computer-based control systems that can be caused by an electromagnetic environment (EME) are functional error modes that involve no component damage. These error modes are collectively known as upset, can occur simultaneously in all of the channels of a redundant control system, and are software dependent. Upset studies performed to date have not addressed the assessment of fault tolerant systems and do not involve the evaluation of a control system operating in a closed-loop with the plant. A methodology for performing a real-time simulation of the closed-loop dynamics of a fault tolerant control system with a simulated plant operating in an electromagnetically harsh environment is presented. In particular, considerations for performing upset tests on the controller are discussed. Some of these considerations are the generation and coupling of analog signals representative of electromagnetic disturbances to a control system under test, analog data acquisition, and digital data acquisition from fault tolerant systems. In addition, a case study of an upset test methodology for a fault tolerant electromagnetic aircraft engine control system is presented

    Laboratory test methodology for evaluating the effects of electromagnetic disturbances on fault-tolerant control systems

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    Control systems for advanced aircraft, especially those with relaxed static stability, will be critical to flight and will, therefore, have very high reliability specifications which must be met for adverse as well as nominal operating conditions. Adverse conditions can result from electromagnetic disturbances caused by lightning, high energy radio frequency transmitters, and nuclear electromagnetic pulses. Tools and techniques must be developed to verify the integrity of the control system in adverse operating conditions. The most difficult and illusive perturbations to computer based control systems caused by an electromagnetic environment (EME) are functional error modes that involve no component damage. These error modes are collectively known as upset, can occur simultaneously in all of the channels of a redundant control system, and are software dependent. A methodology is presented for performing upset tests on a multichannel control system and considerations are discussed for the design of upset tests to be conducted in the lab on fault tolerant control systems operating in a closed loop with a simulated plant

    Status and Current Sensitivity of the CELESTE Experiment

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    The CELESTE experiment uses the heliostats of an old solar farm in the French Pyrenees to detect gamma ray air showers by the atmospheric Cerenkov technique. CELESTE has been operating since November 1999 with an array of 40 heliostats fully instrumented with 1GHz flash ADCs. Significant advances have been made in the detector simulations and in the data analysis techniques. We report here on results from recent observations of the Crab nebula above an energy threshold of 50GeV. The results and simulations illustrate the current sensitivity of the experiment.Comment: 4 pages, 6 figures. To appear in the Proceedings of the Heidelberg Gamma Ray Symposiu

    CXCR4 involvement in neurodegenerative diseases

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    Online Resumes: Optimizing Design to Service Recruiters

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    Despite the increasing number of publications in e-Recruiting, there is still scant research on the specific requirements of online resume fields, in particular from the recruiters’ perspective. In this paper, the fields for resume forms are investigated by analyzing literature, interviewing recruiters and systematically categorizing and content-analyzing the resume fields of the 40 largest Dutch e- Recruiting sites. The findings reflect the main categories currently used in online resume forms: current career status, desired job, education, work experience, extracurricular activities, skills and personal and contact information. These identified online resume fields are discussed in light of prior resume design literature and compared with resume requirements derived from interviewing recruiters. Recommendations for resume design theory and practice are proposed

    Pathological progression induced by the frontotemporal dementia-associated R406W tau mutation in patient-derived iPSCs

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    Mutations in the microtubule-associated protein tau (MAPT) gene are known to cause familial frontotemporal dementia (FTD). The R406W tau mutation is a unique missense mutation whose patients have been reported to exhibit Alzheimer\u27s disease (AD)-like phenotypes rather than the more typical FTD phenotypes. In this study, we established patient-derived induced pluripotent stem cell (iPSC) models to investigate the disease pathology induced by the R406W mutation. We generated iPSCs from patients and established isogenic lines using CRISPR/Cas9. The iPSCs were induced into cerebral organoids, which were dissociated into cortical neurons with high purity. In this neuronal culture, the mutant tau protein exhibited reduced phosphorylation levels and was increasingly fragmented by calpain. Furthermore, the mutant tau protein was mislocalized and the axons of the patient-derived neurons displayed morphological and functional abnormalities, which were rescued by microtubule stabilization. The findings of our study provide mechanistic insight into tau pathology and a potential for therapeutic intervention
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